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KMID : 0986520090090030144
Korean Journal of Endoscrine Surgery
2009 Volume.9 No. 3 p.144 ~ p.148
The Characteristics and Significances of Incidental Focal Uptake by PET-CT in the Thyroid Gland
Kim Ju-Yeon

Moon Hyung-Gon
Jung Eun-Jung
Jeong Tae-Sik
Chung Soon-Il
Jeong Sang-Ho
Jeong Chi-Young
Ju Young-Tae
Lee Young-Joon
Hong Soon-Chan
Choi Sang-Kyung
Ha Woo-Song
Park Soon-Tae
Abstract
Purpose: The increased use of positron emission tomography-computed tomography (PET-CT) has resulted in increased detection of incidentally found thyroid lesions. The purpose of this study was to determine the clinical significance of incidental PET-CT uptake in the thyroid and the characteristics of malignant thyroid lesions.

Methods: A retrospective review was conducted on the patients who were incidentally found to have abnormal uptake of thyroid on PET-CT. The patients¡¯ records were assessed for the demographics, the PET-CT findings, the standard uptake values (SUVmax), the ultrasonography findings, the fine needle aspiration (FNA) cytology and the surgical pathologic findings.

Results: One hundred-ten (4.0%) individuals were identified to have focal (n=35) or diffuse (n=75) thyroid uptake. Thyroid ultrasonography was performed on 29 patients with 35 focal thyroid uptakes, and there was no correlation between the mass size on ultrasonography and the SUVmax on PET-CT. The cytologic diagnosis was available for 26 patients and in 16 (61.53%) patients, the nodule was found to be malignant. The mean and standard deviation of the SUVmax was 5.21¡¾4.08 for the malignant nodules and 8.78¡¾7.32 for the benign nodules. There was no significant difference in the SUVmax between the benign and malignant nodules.

Conclusion: In our study, focal thyroid uptakes incidentally found on PET-CT had a high risk of thyroid malignancy (55.17%). There seems to be no correlation between the SUVmax of the lesion and the risk of malignancy.
KEYWORD
Thyroid, Incidentaloma, PET-CT
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